Structure & Function of Molecular Machines

Three-dimensional structures of human mitochondrial transcription complexes.

We are a research lab located at the University Medical Center Göttingen and at the Max-Planck-Institute for Multidisciplinary Sciences Göttingen.

Our research is aimed at understanding how genetic information is decoded and expressed in human cells, and how this process is linked to human diseaseWe are particularly interested in how genes are activated in mitochondria, the powerhouses of our cells.

To study this, we use ultra-cold electron microscopes (a.k.a. cryo-EM) and high-energy X-Ray beams (a.k.a. X-Ray crystallography) to visualize molecular “nanomachines” in 3D at near-atomic resolution.

News from the Lab

Bernhard Kuhle joins our team!

Bernhard Kuhle joined our lab as a postdoctoral researcher. He did his PhD in Göttingen and then moved to the Scripps Institute in La Jolla, where he...

Hauke is selected for the EMBO Young Investigator Programme

Hauke has been selected to become part of the EMBO Young Investigator Programme. This will provide various types of support to him and the group for a...

Arjun Bhatta wins poster prize at EMBO Meeting in Montenegro

Arjun Bhatta, PhD student in the lab, won a poster prize at the EMBO | FEBS Lecture Course “Mitochondria in life, death and disease” held...

Website artwork by Arjun Bhatta