Structure & Function of Molecular Machines

Three-dimensional structures of human mitochondrial transcription complexes.

We are a research lab located at the University Medical Center Göttingen and at the Max-Planck-Institute for Multidisciplinary Sciences Göttingen.

Our research is aimed at understanding how genetic information is decoded and expressed in human cells, and how this process is linked to human diseaseWe are particularly interested in how genes are activated in mitochondria, the powerhouses of our cells.

To study this, we use ultra-cold electron microscopes (a.k.a. cryo-EM) and high-energy X-Ray beams (a.k.a. X-Ray crystallography) to visualize molecular “nanomachines” in 3D at near-atomic resolution.

News from the Lab

Fernanda Sala joins our team!

We are happy to welcome Fernanda Sala to our team as a postdoctoral researcher! Fernanda did her MSc and PhD in Brazil working with X-Ray ...

Lewis Clark joins our team!

We are excited to welcome Lewis Clark to our team! Lewis did his Master’s at the University of Exeter, and decided to join us for his PhD. We ...

Hauke is selected for the EMBO Young Investigator Programme

Hauke has been selected to become part of the EMBO Young Investigator Programme. This will provide various types of support to him and the group for a ...

Website artwork by Arjun Bhatta