The Hillen Lab https://hillenlab.uni-goettingen.de/ Fri, 03 Jan 2025 11:07:46 +0000 en-US hourly 1 https://wordpress.org/?v=6.8.3 https://hillenlab.uni-goettingen.de/wp-content/uploads/cropped-weblogo-1-32x32.png The Hillen Lab https://hillenlab.uni-goettingen.de/ 32 32 Our paper on human tRNA 3′ processing is published in Nature Structural and Molecular Biology https://hillenlab.uni-goettingen.de/2025/01/03/our-paper-on-human-trna-3-processing-is-published-in-nature-structural-and-molecular-biology/ Fri, 03 Jan 2025 11:07:43 +0000 https://hillenlab.uni-goettingen.de/?p=3056 Our paper on the mechanism of 3′ processing of human mitochondrial and nuclear tRNAs is now published in Nature Structural and Molecular Biology! Congratulations to Arjun, Bernhard, Ryan and Katja and many thanks to Kate Bohnsack for the nice collaboration! Great way to start into 2025!

The post Our paper on human tRNA 3′ processing is published in Nature Structural and Molecular Biology appeared first on The Hillen Lab.

]]>

Our paper on the mechanism of 3′ processing of human mitochondrial and nuclear tRNAs is now published in Nature Structural and Molecular Biology!

Congratulations to Arjun, Bernhard, Ryan and Katja and many thanks to Kate Bohnsack for the nice collaboration!

Great way to start into 2025!

The post Our paper on human tRNA 3′ processing is published in Nature Structural and Molecular Biology appeared first on The Hillen Lab.

]]> New preprint on the structural basis of Nipah virus replication https://hillenlab.uni-goettingen.de/2024/10/04/new-preprint-on-the-structural-basis-of-nipah-virus-replication/ Fri, 04 Oct 2024 14:03:00 +0000 https://hillenlab.uni-goettingen.de/?p=2944 We published a preprint describing cryo-EM structures of the Nipah Virus RNA-dependent RNA polymerase complex, both in its apo and its actively replicating RNA-bound form! Great work by first author Fernanda Sala together with Katja Ditter from our lab and Olexandr Dybkov and Henning Urlaub as collaborators. Click here to […]

The post New preprint on the structural basis of Nipah virus replication appeared first on The Hillen Lab.

]]>

We published a preprint describing cryo-EM structures of the Nipah Virus RNA-dependent RNA polymerase complex, both in its apo and its actively replicating RNA-bound form! Great work by first author Fernanda Sala together with Katja Ditter from our lab and Olexandr Dybkov and Henning Urlaub as collaborators.

Click here to read the paper.

The post New preprint on the structural basis of Nipah virus replication appeared first on The Hillen Lab.

]]> Lea Trost joins as a PhD student https://hillenlab.uni-goettingen.de/2024/09/01/lea-trost-joins-as-a-phd-student/ Sun, 01 Sep 2024 14:09:00 +0000 https://hillenlab.uni-goettingen.de/?p=2956 Lea decided to stay in our group as a PhD student after finishing her Master thesis! We are very happy to have her and wish her good luck and lots of great results!

The post Lea Trost joins as a PhD student appeared first on The Hillen Lab.

]]>

Lea decided to stay in our group as a PhD student after finishing her Master thesis! We are very happy to have her and wish her good luck and lots of great results!

The post Lea Trost joins as a PhD student appeared first on The Hillen Lab.

]]> Arjun Bhatta successfully defended his PhD! https://hillenlab.uni-goettingen.de/2024/08/08/arjun-bhatta-successfully-defended-his-phd/ Thu, 08 Aug 2024 14:05:00 +0000 https://hillenlab.uni-goettingen.de/?p=2952 Arjun Bhatta successfully graduated with distinction as the first PhD student from our lab! Congratulations Arjun and many thanks for your fantastic contributions to our group!

The post Arjun Bhatta successfully defended his PhD! appeared first on The Hillen Lab.

]]>

Arjun Bhatta successfully graduated with distinction as the first PhD student from our lab! Congratulations Arjun and many thanks for your fantastic contributions to our group!

The post Arjun Bhatta successfully defended his PhD! appeared first on The Hillen Lab.

]]> New preprint on the mechanism of tRNA 3′ processing https://hillenlab.uni-goettingen.de/2024/04/04/new-preprint-on-the-mechanism-of-trna-3-processing/ Thu, 04 Apr 2024 13:49:00 +0000 https://hillenlab.uni-goettingen.de/?p=2938 We published a preprint on the molecular basis of nuclear and mitochondrial tRNA 3′ processing by the endonuclease ELAC2! This was a great joint effort by shared-first authors Arjun, Bernhard and Ryan and a collaboration with the lab of Kate Bohnsack (UMG). Click here to read the paper.

The post New preprint on the mechanism of tRNA 3′ processing appeared first on The Hillen Lab.

]]>

We published a preprint on the molecular basis of nuclear and mitochondrial tRNA 3′ processing by the endonuclease ELAC2!

This was a great joint effort by shared-first authors Arjun, Bernhard and Ryan and a collaboration with the lab of Kate Bohnsack (UMG).

Click here to read the paper.

The post New preprint on the mechanism of tRNA 3′ processing appeared first on The Hillen Lab.

]]> Paper on the Chloroplast RNA polymerase structure published https://hillenlab.uni-goettingen.de/2024/03/07/paper-on-the-chloroplast-rna-polymerase-published/ Thu, 07 Mar 2024 14:41:00 +0000 https://hillenlab.uni-goettingen.de/?p=2922 The post Paper on the Chloroplast RNA polymerase structure published appeared first on The Hillen Lab.

]]>

Our paper on the structure of the multi-subunit chloroplast RNA polymerase (PEP) was published in Molecular Cell! Great collaboration with the Lab of Thomas Pfannschmidt. Congratulations to the joint-first authors Freddy and Paula!

Link to the paper and to a press release by the MPI-NAT.

The post Paper on the Chloroplast RNA polymerase structure published appeared first on The Hillen Lab.

]]> Lea Trost starts as a Master Student in our lab! https://hillenlab.uni-goettingen.de/2023/12/20/lea-trost-starts-as-a-master-student-in-our-lab/ Wed, 20 Dec 2023 21:49:01 +0000 https://hillenlab.uni-goettingen.de/?p=2885 Lea Trost, a Master Student from the Molecular Lifesciences program, joined our lab for her Master thesis. We are excited to have you Lea and wish you lots of fun and good results!

The post Lea Trost starts as a Master Student in our lab! appeared first on The Hillen Lab.

]]>

Lea Trost, a Master Student from the Molecular Lifesciences program, joined our lab for her Master thesis. We are excited to have you Lea and wish you lots of fun and good results!

The post Lea Trost starts as a Master Student in our lab! appeared first on The Hillen Lab.

]]> ERC Starting Grant “MitoRNA” is funded https://hillenlab.uni-goettingen.de/2023/09/05/our-erc-starting-grant-mitorna-is-funded/ Tue, 05 Sep 2023 10:00:45 +0000 https://hillenlab.uni-goettingen.de/?p=2827 Our proposal for a Starting Grant from the European Research Council was selected for funding! In the project “MitoRNA”, we will explore the mechanisms underlying the RNA life cycle in human mitochondria. Read more in the press release by the UMG (German) or the MPI-NAT (English).

The post ERC Starting Grant “MitoRNA” is funded appeared first on The Hillen Lab.

]]>

Our proposal for a Starting Grant from the European Research Council was selected for funding! In the project “MitoRNA”, we will explore the mechanisms underlying the RNA life cycle in human mitochondria. Read more in the press release by the UMG (German) or the MPI-NAT (English).

The post ERC Starting Grant “MitoRNA” is funded appeared first on The Hillen Lab.

]]> Ana Vučković starts as a PhD student in the group! https://hillenlab.uni-goettingen.de/2023/06/01/ana-vuckovic-starts-as-a-phd-student-in-the-group/ Thu, 01 Jun 2023 14:10:45 +0000 https://hillenlab.uni-goettingen.de/?p=2815 Ana Vučković started her PhD in our group! She is a student from the International Max Planck Research School (IMPRS) Molecular Biology and previously did her Master thesis work in our lab. We are very happy and excited that you decided to stay in the team!

The post Ana Vučković starts as a PhD student in the group! appeared first on The Hillen Lab.

]]>

Ana Vučković started her PhD in our group! She is a student from the International Max Planck Research School (IMPRS) Molecular Biology and previously did her Master thesis work in our lab. We are very happy and excited that you decided to stay in the team!

The post Ana Vučković starts as a PhD student in the group! appeared first on The Hillen Lab.

]]> Saruby Sharma joins our team! https://hillenlab.uni-goettingen.de/2023/05/24/saruby-sharma-joins-our-team/ Wed, 24 May 2023 14:05:06 +0000 https://hillenlab.uni-goettingen.de/?p=2803 Saruby Sharma, a student from the International Max Planck Research School (IMPRS) Molecular Biology, joined our lab as a PhD student! She has expertise in membrane protein biochemistry. Welcome Saruby, we are exicted to have you!

The post Saruby Sharma joins our team! appeared first on The Hillen Lab.

]]>

Saruby Sharma, a student from the International Max Planck Research School (IMPRS) Molecular Biology, joined our lab as a PhD student! She has expertise in membrane protein biochemistry. Welcome Saruby, we are exicted to have you!

The post Saruby Sharma joins our team! appeared first on The Hillen Lab.

]]>